1 min read

ID: 1039570

Short Link: https://gregory-ms.com/articles/1039570/

Discovery Date: 27 October 2022, 11:10:12 UTC

Published Date: 2022-10-27 10:00:00

Source: PubMed

Link: https://pubmed.ncbi.nlm.nih.gov/36294458/?fc=20210216052009&ff=20221027071011&v=2.17.8

Manual Selection: true

Machine Learning Gaussian Naive Bayes Model: false

Abstract

Bruton’s tyrosine kinase (BTK) is an important protein belonging to the tyrosine kinase family that plays a key role in the intracellular signaling and proliferation, migration, and survival of normal and malignant B-lymphocytes and myeloid cells. Understanding the role of BTK in the B-cell signaling pathway has led to the development of BTK inhibitors (BTKi) as effective therapies for malignancies of myeloid origin and exploration as a promising therapeutic option for other cancers. Given its…

Noun Phrases in Title

  • Bruton's Tyrosine Kinase Inhibitors
  • The Next Frontier
  • B-Cell-Targeted Therapies
  • Cancer
  • Autoimmune Disorders
  • Multiple Sclerosis
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