1 min read

ID: 751509

Short Link: https://gregory-ms.com/articles/751509/

Discovery Date: 23 July 2022, 13:40:05 UTC

Published Date: 2022-07-22 10:00:00

Source: PubMed

Link: https://pubmed.ncbi.nlm.nih.gov/35868215/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=10guX6I3SqrbUeeLKSTD6FCRM44ewnrN2MKKTQLLPMHB4xNsZU&fc=20210216052009&ff=20220723094004&v=2.17.7

Manual Selection: true

Machine Learning Gaussian Naive Bayes Model: false

Abstract

Multiple sclerosis (MS), an immune-mediated and neurodegenerative disorder of the central nervous system (CNS), is characterized by infiltrating myelin-reactive T lymphocytes and demyelinating lesions. Experimental autoimmune encephalomyelitis (EAE) is a well-established animal model used to study MS. To explore the impact of chemokine receptor CCR1 blockade in EAE and the underlying mechanisms, we used CCR1 antagonist J-113863 in PLP(139-151)-induced EAE in SJL/J mice. Following EAE induction,…

Noun Phrases in Title

  • CCR1
  • J-113863 corrects
  • the imbalance
  • pro-
  • anti-inflammatory cytokines
  • a SJL/J mouse model
  • relapsing-remitting multiple sclerosis
This is an independent project that runs on the good will of volunteers

You can help by spreading the word or by donating what you can to pay for the server costs.