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Systematic review and network meta-analysis (NMA) for cladribine tablets in achieving sustained disability improvement (SDI) in multiple sclerosis

Neurol Neurochir Pol. 2022 Nov 24. doi: 10.5603/PJNNS.a2022.0068. Online ahead of print. ABSTRACT INTRODUCTION: This study was performed to compare probabilities of SDI on the Expanded Disability Status Scale (EDSS) in patients …
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PubMed manual

Oral Administration of Myelin Oligodendrocyte Glycoprotein Attenuates Experimental Autoimmune Encephalomyelitis through Induction of Th2/Treg Cells and Suppression of Th1/Th17 Immune Responses

Curr Issues Mol Biol. 2022 Nov 18;44(11):5728-5740. doi: 10.3390/cimb44110388. ABSTRACT Multiple Sclerosis (MS) is a demyelinating autoimmune disorder of the central nervous system (CNS). Experimental autoimmune encephalomyelitis …
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PubMed manual

Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine

ACS Chem Neurosci. 2022 Nov 21. doi: 10.1021/acschemneuro.2c00365. Online ahead of print. ABSTRACT Acute activation of innate immune response in the brain, or neuroinflammation, protects this vital organ from a range of external …
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Stem Cells

The Immunomodulatory Potential Role of Mesenchymal Stem Cells in Diseases of the Central Nervous System

Neurodegener Dis. 2022 Nov 17. doi: 10.1159/000528036. Online ahead of print. ABSTRACT INTRODUCTION: Several studies indicate the role of mesenchymal stem cells (MSCs) as an important tool in regenerative medicine associated with …
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Ferulic Acid Ameliorates Cell Injuries, Cognitive and Motor Impairments in Cuprizone-Induced Demyelination Model of Multiple Sclerosis

Cell J. 2022 Nov 2;24(11):681-688. doi: 10.22074/cellj.2022.8261. ABSTRACT OBJECTIVE: Ferulic acid (FA) is a phenolic compound that exhibits neuroprotective effects in the central nervous system (CNS). This study was conducted to …
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Unwrapping the “black box” of balance training in people with multiple sclerosis – a descriptive systematic review of intervention components, progression, and intensity.

Background Delineating the specific components of the existing balance training interventions in people with multiple sclerosis (PwMS) may contribute to a framework for future design and reporting of such interventions. Thus, we …
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MS & Rel. Disorders auto

Oligoclonal IgM bands are a promising biomarker for long-term cognitive outcomes in multiple sclerosis

Background The presence of lipid-specific oligoclonal IgM bands (LS-OCMB) in cerebrospinal fluid is associated with a more severe clinical multiple sclerosis (MS) course. Objective To investigate LS-OCMB as a prognostic biomarker …
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MS & Rel. Disorders auto

More Gain, Less Pain: How Resistance Training Affects Immune System Functioning in Multiple Sclerosis Patients: A Review

Multiple sclerosis (MS) is characterized by a complex etiology that is mirrored by the perplexing and inconsistent treatment responses observed across different patients. Although epigenetic research has garnered rightful interest …
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MS & Rel. Disorders auto

The effects of bupropion on sexual dysfunction in female patients with multiple sclerosis: a double-blind randomized clinical trial

Background Sexual dysfunction (SD) is one of the most common complications of multiple sclerosis (MS). The aim of this study was to evaluate the effects of bupropion on SD among female patients with MS. Methods This double-blind …
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MS & Rel. Disorders auto

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